About
Dominnique Karetsos

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Visionary Leadership in Sexual Health and Women's Health Technology

Dominnique Karetsos is a serial entrepreneur, venture general partner, and pioneering force in sexual health and technology—a term she coined during the industry’s early, undefined days. For over a decade, she has been instrumental in establishing innovation, investment, and education as the foundational pillars of a thriving sexual health ecosystem. Her work has helped elevate healthy sexuality from a niche economy into a global movement rooted in change, inclusivity, and empowerment.

Her journey in sexual health began as the founder and venture-backed CEO of Healthy Pleasure Group, where she launched groundbreaking innovations at the intersection of sexual health and technology. She guided these ventures to expand market share, maximize investment opportunities, and create meaningful, lasting impact. With a keen eye for emerging trends and market shifts, Dominnique co-founded Amboy Street Ventures in 2020—the first and only investment fund dedicated to sexual health and women’s health technology. As General Partner for Fund I and Venture Partner for Fund II, she has overseen the fund’s growth from $20 million to a robust portfolio of pioneering investments. Through her leadership, Dominnique is driving not only financial performance but also societal permission and behavioral change in these critical sectors.

Dominnique's Achievements

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Education has always been a cornerstone of Dominnique’s mission, forming the third pillar alongside innovation and investment. As a clinical sexologist and sex educator, she empowers individuals to embrace their sexual agency and wellbeing, ensuring that knowledge and understanding remain at the heart of the movement she leads. Her expertise is built on a strong, multidisciplinary foundation, with degrees in International Marketing and Management, Advanced Supply Chain Management, and a Master’s in Maritime and International Trade. This unique blend of formal education and real-world experience has allowed her to collaborate with global brands and sexual health businesses, helping them uncover their competitive edge, grow market share, and achieve meaningful, sustainable impact.

Dominnique’s contributions extend beyond entrepreneurship and education. For three years, she has served as a UN Women Delegate for CSW65/67/68 and the Future of Innovation—a role that has deepened her insight into global socio-political challenges. Through this work, she has engaged in critical conversations on innovation, gender equality, and systemic change, aligning her efforts with her unwavering north star: sexual justice.

A passionate advocate for sexual justice, Dominnique actively supports safe houses for sex-trafficked girls and women in Southern Africa. Through her foundation, Her 100—a subsidiary of Merchants of Light—she is dedicated to helping survivors reclaim their dignity and safety. The foundation provides secure housing, comprehensive healthcare, education, and essential resources, enabling women and girls to heal from trauma and rebuild their lives with strength and confidence. Further extending her commitment, Dominnique serves as Chief Impact Officer for the Blue Rose Foundation, where she continues to champion the rights and wellbeing of society’s most vulnerable and drive systemic change.

Dominnique’s influence resonates far beyond the boardroom. As a seasoned global speaker, she is a regular presence on international stages, delivering keynotes and participating in panels at renowned forums such as Management Today, Women Innovation Health Summits, Sigma Health Tech Malta, sTARTUp Day Estonia, SXSW London, and the Women in Tech Global Summit Paris. Her thought leadership has been featured in major publications including The New York Times, Fortune, Forbes, The Telegraph, and Oprah Magazine, solidifying her reputation as a trusted voice and catalyst for change in the industry.

Driven by her passion for advocating agency in all aspects of sex, tax, and money, Dominnique envisions a more inclusive world where sexual health and autonomy are fundamental rights. Her life’s work transcends the business realm; it is a mission to elevate healthy sexualities as the elixir to a kinder, safer, and healthier humanity.